SCO 5-6, Zirakpur-Panchkula-Kalka Hwy, near Hotel Sunpark, Wadhawa Nagar, Dhakoli, Zirakpur, Punjab 140603

Orlistat 120mg Tablet

Orlistat 120mg Tablet - Manufacturers & Suppliers - Third Party Contract Manufacturing - PCD Pharma Franchise

Orlistat 120mg Tablet

Composition : ORLAK-120

Packing : 10x10

Price : Rs. 3900

Please Contact Us

ORLAK-120 (Orlistat 120mg Tablet Manufacturer & Supplier)

Orlak 120 contains orlistat 120 mg. Orlistat is a lipase inhibitor used in the treatment of obesity that works by inhibiting fat-metabolizing enzymes.
• Obesity management
• Weight gain 
• Weight maintenance

  Dosage : As directed by physician
  Mechanism of Action
Orlistat is a potent and selective inhibitor of various lipase enzymes responsible for the metabolism of fat. It acts in the gastrointestinal (GI) tract via covalent binding to the serine residues located on the active site of both gastric and pancreatic lipase. When orlistat is taken with food containing fat, it partially inhibits the hydrolysis of triglycerides. This decreases absorption of monoaclglycerides and free fatty acids, contributing to weight maintenance and weight loss.

The systemic absorption and exposure of orlistat is low, however, systemic absorption of the drug is not required for orlistat activity.After an oral dose with 360 mg of radiolabeled orlistat, plasma radioactivity achieved a peak at about 8 hours.
Volume of distribution cannot be obtained because the absorption of orlistat is minimal. Orlistat is minimally distributed to erythrocytes and is primarily bound to proteins.
After single oral dose of radiolabled orlistat in both normal weight and obese volunteers fecal excretion of the unabsorbed drug was found to be the major route of elimination with <2% urinary excretion.
• Malabsorption.
• Hypersensitivity to orlistat.
• Reduced gallbladder function (e.g. after cholecystectomy)
• Pregnancy and breastfeeding.
• Anorexia and Bulimia.
• Use caution with: obstructed bile duct, impaired liver function, and pancreatic disease
• Pregnant and lactation
• Patient with diabetes
• Patient with allergic reaction
• Tenderness
• Dark urine