Gliclazide Me ormin 80mg 500mg Tablet

Gliclazide 80 mg and Metformin 500 mg Tablet- This tablet belongs to the class of medicines that help in treating diabetes. It helps in treating Type 2 diabetes, which is a chronic condition that cannot be cured for life. However, health issues can be managed with the use of correct pharmaceutical salts. Gliclazide and Metformin Tablets are a combination of two anti-diabetic medicines. 

People facing type 2 either face a condition under which the body reduces the production of insulin, or if the production is good, the body is unable to recognize it. Under the condition, blood glucose drops, and irregular body symptoms such as excessive urine, sweating, thirst, and hunger may develop. Diabetes may lead to several other health problems, such as low immunity, eye infections, diabetic foot, and the appearance of wounds after the intake of excessive sugar. Heart attacks and strokes are very common in diabetes. 

Gliclazide 80 mg and Metformin 500 mg tablets are a combination of Gliclazide and Metformin. Gliclazide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). Gliclazide belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating β cells of the pancreas to release insulin. Sulfonylureas increase both basal insulin secretion and meal-stimulated insulin release. Arlak Corazon offers Gliclazide and Metformin Tablets under the brand name Z-GLIC M.

 Indication of Gliclazide and Metformin Tablet

The indications of Gliclazide and Metformin Tablets are mentioned as follows:

• Treatment of NIDDM
• Type 2 Diabetes Mellitus

Dosage-  As directed by the Physician

Working Mechanism of Gliclazide and Metformin Tablet

Below are the details mentioned about the working mechanism of the salt. 

Gliclazide

Gliclazide binds to the β-cell sulfonylurea receptor (SUR1). This binding subsequently blocks the ATP-sensitive potassium channels. The binding results in closure of the channels and leads to a resulting decrease in potassium efflux, leading to depolarization of the β cells. 

Metformin

Metformin inhibits mitochondrial complex I activity, which is responsible for its potent antidiabetic effect. It decreases gluconeogenesis in the liver and also decreases the intestinal absorption of glucose. It also improves the sensitivity of insulin.

What are the Benefits of Using Gliclazide and Metformin Tablets?

The medicinal benefits of using Gliclazide and Metformin Tablets are mentioned as follows:

• Helps control high blood sugar levels in people with Type 2 diabetes.
• Gliclazide 80 mg increases insulin release from the pancreas.
• Metformin 500 mg reduces extra sugar production in the liver.
• Improves the body’s response to insulin.
• Helps lower fasting and post-meal blood sugar levels.
• Reduces the risk of diabetes-related complications.

Safety Measures and Precautions While Using Gliclazide and Metformin Tablets

• A list of safety measures and precautions has to be followed during the use of Gliclazide and Metformin Tablets; a few have been mentioned as follows:
• Discuss your previous and ongoing health issues, if you have any.
• Take Gliclazide and Metformin Tablets as per the doctor's suggestions.
• Avoid increasing and decreasing the dosage on your own; consult your healthcare professional first.
• If you’re pregnant or breastfeeding, avoid using Gliclazide and Metformin Tablets; consult your doctor before doing so.
• Monitor your blood sugar level regularly while you are taking this medicine.
• It may cause hyperglycemia (Low levels of blood sugar)

How to Store the Gliclazide and Metformin Tablets?

Follow the instructions mentioned below:

• Store the Gliclazide 80 mg and Metformin 500 mg Tablet in a cool, dry place (25-28 °C)
• Protect it from light and moisture.
• Keep it away from the children and pets.
• Do not freeze the tablets.
• Do not use the Gliclazide and Metformin Tablets after the expiry date.