Dabigatran is used to prevent stroke and harmful blood clots(such as in your legs or lungs) if you have a certain type of irregular heartbeat . Dabigatran is also used to treat blood clots in the veins of your legs and to reduce the risk of them occurring again. This medication may also be used to prevent these blood clots from forming after surgery. Dabigatran is an anticoagulant that works by blocking a certain substance in your blood.
Uses of DABIGATRAN ETEXILATE
Prevention of blood clot formation, deep vein thrombosis, pulmonary embolism.
DABIGATRAN ETEXILATE belongs to a class of drugs known as anticoagulants or blood thinners. DABIGATRAN ETEXILATE is primarily used to prevent and treat the risk of stroke and heart attack by reducing blood clot formation. Besides this, it also reduces the risk of getting clots in people who have undergone knee or hip replacement surgeries. DABIGATRAN ETEXILATE works by stopping the action of clotting factor (thrombin). This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots formation.
In-Depth Precautions and Warning
If you are known to be allergic to DABIGATRAN ETEXILATE or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using DABIGATRAN ETEXILATE. DABIGATRAN ETEXILATE is not recommended for children less than 18 years of age as the Safety and effectiveness have not been established. If you have an artificial heart valve, stomach ulcer, kidney/liver problems, high blood pressure, or bleeding problems, inform your doctor before taking DABIGATRAN ETEXILATE. You should inform the doctor that you are taking DABIGATRAN ETEXILATE if you are due to undergo surgery. Avoid consumption of alcohol while taking DABIGATRAN ETEXILATE as it may increase the risk of stomach bleeding.
Drug-Drug Interactions: DABIGATRAN ETEXILATE may interact with medicines to reduce blood clotting (warfarin, phenprocoumon, acenocoumarol, heparin, clopidogrel, prasugrel, ticagrelor, rivaroxaban), medicines to treat abnormal heartbeats (amiodarone, dronedarone, quinidine, verapamil), medicines to treat fungal infections (ketoconazole, itraconazole), medicines to prevent organ rejection after transplantation (tacrolimus, cyclosporine) antiviral or HIV medicines (ritonavir, glecaprevir, pibrentasvir), antibiotics (rifampicin, clarithromycin), pain reliever (aspirin, ibuprofen, diclofenac), antiepileptic drugs (carbamazepine, phenytoin).
Drug-Food Interactions: DABIGATRAN ETEXILATE may interact with St. John’s wort, herbal medicine for depression.
Drug-Disease Interactions: DABIGATRAN ETEXILATE should be used with caution in patients with kidney, liver, or bleeding problems, heart problems, and unstable blood pressure.