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Vildaglip n 50 mg Tablet

Vildaglip n 50 mg Tablet - Manufacturers & Suppliers - Third Party Contract Manufacturing - PCD Pharma Franchise

Vildaglip n 50 mg Tablet

Composition : Z-VIL-50

Packing : 10X15

Price : Rs. 2250

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Z-VIL-50 (Vildaglip n 50 mg Tablet)

Z-VIL-50 is composed of Vildagliptin 50mg. Vildagliptin is a DPP-4 inhibitor, increases the release of insulin from the pancreas and decreases the hormones that raise blood sugar levels.  
  Indications
•    Type 2 diabetes Mellitus
•     Maintains the blood sugar level
  Mechanism of action
Vildagliptin inhibits the inactivation of GLP-1 and GIP by DPP-4, which allows GLP-1 and GIP to initiate the secretion of insulin in the beta cells and suppress glucagon release by the alpha cells of the islets of Langerhans in the pancreas
  Dosage : As prescribed by the physician
  Pharmacology
Absorption
Vildagliptin is rapidly absorbed with an oral bioavailability of greater than 90% followed by oral administration. 
Distribution
Vildagliptin is minimally bound to plasma proteins (9.3%) and, on the basis of a volume of distribution of 71 L, it is considered to distribute extensively into extra vascular spaces. 
Excretion
 Approximately one-quarter of a dose of vildagliptin is excreted unchanged by the kidneys, and the remainder metabolised by hydrolysis.  
  Precautions
Inform your physician, if you are
• Allergic to this medication or any of the other ingredients of this medication.
•  Pregnant, planning to become pregnant, or breastfeeding.
• Any disease of the pancreas (such as pancreatitis, which is a condition where the pancreas is inflamed)
• Gallstones, drink alcohol often or have very high levels of triglycerides (a type of cholesterol) in your blood. 
• Have or had diabetic keto acidosis where there is a build-up of acid in the blood because the body is breaking down fat instead of sugar before
• Kidney or liver problems

  Contraindications
• Congestive heart failure  
• Acute or chronic metabolic acidosis, including lactic acidosis or diabetic keto acidosis


Introduction