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Me ormin 1000mg Tablet

Me ormin 1000mg Tablet - Manufacturers & Suppliers - Third Party Contract Manufacturing - PCD Pharma Franchise

Me ormin 1000mg Tablet

Composition : ZULIP-1000SR

Packing : 10x10

Price : Rs. 354

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 Introduction
Zulip-1000 SR Tablet contains metformin. It is also an oral antidiabetic drug which belongs to biguanide class which is the first line treatment for type 2 diabetes mellitus. It causes suppression of glucose production by liver.
  Indication
• First line treatment for type 2 diabetes
• Metformin is used in pre-diabetes
• PCOS (polycystic ovary syndrome)
• Gastrointestinal diabetes
  Dosage : Once daily or as directed by the physician
  Mechanism of action
It decreases gluconeogenesis in liver and also decreases the intestinal absorption of glucose. It also improves the sensitivity of insulin.
  Pharmacology
Metformin
Absorption
In fasting condition of the patients, the drug bioavailability is about 50% to 60%. Food decreases the absorption of drug.
Distribution
The volume of distribution is 654±358 L. It rarely bonds to plasma protein. It does not follow hepatic metabolism.
Excretion
It is excreted in unchanged form in urine
  Contraindications
• Use is contraindicated in pregnant patient
• In lactating mothers
• Renal dysfunction
• Patient undergoing radiological studies
• Acute or chronic metabolic acidosis
  Precautions
• Renal and hepatic impairment
• Avoid alcohol consumption
• Hypoglycemic episodes
• Lung and liver disease