Glimipride 2mg Tablet - Manufacturers & Suppliers - Third Party Contract Manufacturing - PCD Pharma Franchise
Copride 2 Tablet contains Glimepiride. It is an anti-diabetic drug belongs to sulphonylurea class. It is long acting oral anti-diabetic drug.
• Mainly used in type 2 diabetes
• Adjunct therapy to improve hyperglycemia
Dosage : Once a day
Mechanism of action
The drug stimulates the pancreatic beta cells that release insulin. The drug bound to sulphonyl urea receptor in the pancreatic cells closing of potassium channel which causes release of insulin. This in turn lowers the blood glucose level.
After oral administration the drug peak concentration achieves in 2-3 hrs. Co-administration of the drug with food causes decrease in the concentration of the drug by 8-9%
The drug is well distributed in the body by binding protein binding about 99.5%. The drug is metabolized oxidative biotransformation by oral administration.
The drug follows renal excretion
• Patient with the history of hypersensitivity to drug
• Can cause hypoglycemia
• Increased the risk of cardiac mortality
• In pregnant patients