Cilnidipine a novel calcium-channel blocker, is prescribed for the medical management of hypertension in adults.
Cilnidipine is a dihydropyridine class of calcium-channel blocker. Cilnidipine prevents intracellular calcium influx and results in vasodilatation. Cilnidipine possesses superior selectivity for vascular smooth muscle cells.
Cilnidipine is contraindicated in patients with severe aortic stenosis, cardiogenic shock, recent history of unstable angina or MI, heart failure and hypotension. Do not discontinue Cilnidipine abruptly to avoid withdrawal symptoms.
Other Drug Interactions
Cilnidipine can interact with aldesleukin, quinidine, phenytoin, rifampicin, erythromycin, other anti-hypertensive drugs and anti-psychotic drugs.