BRAND NAME :- ZULIP-G1 FORTE
COMPOSITION :-GLIMEPRIDE AND METFORMIN HCL (ER) TABLET
MEDICATION USED FOR :–
Glimepride used with a proper diet and exercise program to control high blood sugar in people with type 2 diabetes. Glimipiride may also be used with other diabetes medications. Controlling high blood sugar helps prevent kidney damage ,blindness , nerve problems , loss of limbs and sexual function problems .Glimepride helps control blood sugar 4 when used along with a healthy diet and exercise .Proper control of diabetes may also lesser your risk of a heart attack or stroke . Glimepride belongs to the class of drug known as sulfonylurea’s.
Glimepride lower blood sugar by causing the release of your body’s natural insulin . Metformin is used with a proper diet and exercise program and possible with other medication to control high blood sugar . metformin hydrochloride (ER) used in patient with type 2 diabetes . Controlling high blood sugar helps prevent kidney damage , blindness , nerve problems ,loss of limbs and sexual function problem . Metformin is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus . Metformin is sometime used together with insulin or other medication , but it is not for treating type & diabetes .
MECHANISM OF ACTION
Glimepride primarily lower blood glucose by stimulating the release of insulin from pancreatic beta cells. Glimepride used when diet exercise and weight reduction have not been found to control blood sugar well enough on their own. Glimipiride increase the amount of insulin released by the pancreas and helps the body use insulin more efficiently . Metformin is apreparation of Metformin Hydrochloride . Metformin Hydrochloride a biguanide type oral anti hyperglycemic agent used in the management of type 2 diabetes mellitus. Metformin Hydrochloride (ER) lower both and postprandial plasma glucose .
Metformin mechanism of action is different from those of sulfonylurea’s and it does not produce hypoglycemia .Metformin decrease hepatic glucose production , decrease intestinal absorption of glucose , and improves insulin sensitivity by increasing peripheral glucose uptake and utilization.